IONPURE LX-HI Hot Water Sanitizable CEDI Module Electrodeionization System for Pharmaceutical Ultrapure Water Production

　　The IONPURE LX-HI series is a hot water sanitizable electrodeionization system for high purity water production,targeting pharmaceutical and biotechnology processes.Available in models LXM04HI-3 through LXM45HI-3,these CEDI modules operate continuously at 60°C and withstand hot water sanitization up to 85°C,producing water with conductivity below 0.1µS/cm and 90–95%recovery.

　　What Is a Hot Water Sanitizable CEDI Module?

　　A hot water sanitizable CEDI module is an electrodeionization stack designed to produce high-purity water using electrical current,ion-exchange membranes,and resin,while tolerating periodic elevated-temperature disinfection cycles.Unlike chemical sanitization,hot water sanitization uses heat alone to control microbial growth,eliminating chemical handling and residue risks.

　　Standard CEDI modules cannot endure repeated temperatures above 60°C without membrane or resin damage.The LX-HI series incorporates a proprietary material set and sealing design that permits sanitization at 85°C and continuous production at 60°C,making it suitable for pharmaceutical purified water and water-for-injection pretreatment loops where microbial control is critical.

　　Key Specifications

　　Available Models:

　　IP-LXM04HI-3

　　IP-LXM10HI-3

　　IP-LXM18HI-3

　　IP-LXM24HI-3

　　IP-LXM3OHI-3

　　IP-LXM45HI-3

　　Product Water Conductivity:<0.1µS/cm

　　Water Recovery:90–95%

　　Continuous Operating Temperature:Up to 60°C

　　Hot Water Sanitization Temperature:Up to 85°C(+5°C tolerance)

　　Maximum Sanitization Pressure:2.1 bar

　　Continuous Operating Pressure(Max):7 bar

　　Pressure Drop:1.4–2.1 bar

　　Feed Water Conductivity:<40µS/cm

　　Feed Water Temperature:5–60°C

　　Feed Water Pressure:1.4–7 bar

　　Maximum Feed Water Hardness:<1.0 ppm(as CaCO₃)

　　Maximum Feed Water Silica:<1.0 ppm

　　Maximum Free Chlorine:<0.02 ppm

　　DC Power Supply:0–565 VDC,1–10 A

　　Sanitization Cycle Durability:150+cycles with no measurable performance degradation

　　Wetted Materials Compliance:FDA 21 CFR

　　Sealing:Double O-ring design

　　Certifications:CE,ISO 9001,ISO 14000,Halal

　　Dimensions(L x C):300.0–907.3 mm×189.7–796.3 mm(varies by model)

　　Mounting Environment:Indoor,ambient temperature≤45°C,avoid direct sunlight

　　Specifications per manufacturer datasheet and factory acceptance test records.

　　Technical Highlights

　　Instant hot water sanitization without temperature ramping eliminates slow warm-up and cool-down phases.The proprietary instant hot water technology allows direct introduction of 85°C water into the module,reducing overall sanitization cycle time and plant downtime compared to conventional heat-sanitizable systems that require gradual temperature transitions.

　　Double O-ring seal ensures zero leakage during thermal cycling.The dual-seal design accommodates material expansion and contraction during repeated heat-up and cool-down cycles,preventing bypass or external leakage across the full rated pressure and temperature range.

　　Over 150 sanitization cycles without performance loss confirms long-term reliability.Factory validation data demonstrates that product water quality,salt rejection,and pressure drop remain stable after more than 150 hot water sanitization events,supporting multi-year service life in demanding pharmaceutical water systems.

　　Concentrate recirculation and salt injection are not required.The module operates with a single-pass concentrate stream without supplementary brine injection or recirculation pumps,simplifying system piping,reducing auxiliary equipment,and lowering both capital and operating expenditures.

　　FDA-compliant wetted materials cover all components in contact with process water,meeting the requirements of 21 CFR for indirect food additives used in pharmaceutical water generation and bioprocessing applications.

　　Applications

　　Pharmaceutical purified water(PW)loops:Continuously produces water meeting USP<645>conductivity limits(<1.3µS/cm at 25°C)with hot water sanitization capability that eliminates the need for chemical disinfectants,reducing system downtime and chemical validation burden.

　　Water-for-injection(WFI)pretreatment:Supplies high-purity water to distillation units or as part of a cold WFI generation system,with the module's 85°C sanitization temperature aligning with pharmacopeial sanitization strategies for microbial control.

　　Biotechnology process water:Provides low-endotoxin,low-conductivity water for cell culture media preparation and buffer makeup;the periodic heat sanitization helps maintain sub-10 CFU/100 mL bioburden levels without introducing oxidizing chemicals that stress downstream membrane filters.

　　High-purity water for hemodialysis concentrate mixing:Delivers<0.1µS/cm water for bicarbonate and acid concentrate preparation,with the heat-disinfection feature supporting infection control protocols in central dialysis fluid delivery systems.

　　Semiconductor and electronics rinsing water(non-critical rinses):Serves as pre-polishing step,achieving 90–99%silica removal while operating with 90–95%recovery,significantly reducing reject water volume compared to reverse osmosis alone.

　　Selection Guidance

　　Suitable for pharmaceutical and biotech facilities requiring hot water sanitization at≥80°C for microbial control without chemical additives.The LX-HI is designed for systems where the entire pretreatment and generation loop is heat-sanitized,and the module must withstand repeated exposure to 85°C without performance drift.

　　Suitable for RO permeate polishing where the feed water meets the specified quality limits(conductivity<40µS/cm,hardness<1 ppm,silica<1 ppm,free chlorine<0.02 ppm).Under these conditions,the module operates maintenance-free between scheduled sanitization events.

　　Not recommended for feed water with hardness or silica exceeding 1 ppm without upstream softening or silica removal.Exceeding these limits results in scale formation on the concentrate compartment and irreversible loss of salt rejection.Install a softener and,if necessary,a degasifier to meet the inlet specification before the CEDI stage.

　　Not suitable as a standalone solution for ultrapure water requiring resistivity>18 MΩ·cm.The product water conductivity of<0.1µS/cm(>10 MΩ·cm)may require further polishing through mixed-bed deionization or ultrafiltration to achieve Type E-1 or ASTM Type I ultrapure water specifications.

　　FAQ

　　1.How much does an IONPURE LX-HI CEDI module cost?

　　Prices range from approximately 8,500to24,000 USD depending on the model(LXM04HI-3 through LXM45HI-3)and quantity.Prices fluctuate due to exchange rates,tariffs,and factory adjustments.Contact Beijing Zhongping Technology for a current,detailed quotation matching your flow rate and configuration.

　　2.What is the delivery time,and are IONPURE LX-HI modules in stock?

　　Manufacturer standard lead time is 4 to 6 weeks.Beijing Zhongping Technology maintains inventory of commonly specified models for expedited fulfillment,dispatching in-stock modules within 2 to 3 business days.

　　3.What certifications do IONPURE LX-HI electrodeionization modules meet?

　　The modules carry CE marking,and the manufacturing facility holds ISO 9001 and ISO 14000 certifications.Additionally,the product holds Halal certification,ensuring suitability for pharmaceutical and food-processing applications in relevant markets.

　　4.Do the wetted materials of the IONPURE LX-HI comply with FDA requirements?

　　Yes,all process-contact materials in the LX-HI module meet FDA 21 CFR requirements for indirect food additives,which is verified by the manufacturer.This compliance supports use in pharmaceutical water systems and bioprocessing where extractables and leachables must be controlled.

　　5.What are the minimum feed water quality requirements for the electrodeionization system?

　　The inlet stream must be RO permeate or equivalent with conductivity<40µS/cm,hardness<1.0 ppm(as CaCO₃),silica<1.0 ppm,and free chlorine<0.02 ppm.Feed water temperature must stay between 5°C and 60°C,and inlet pressure between 1.4 and 7 bar.Operating outside these limits accelerates fouling,scale formation,and membrane degradation.

　　6.How is hot water sanitization performed,and what are the temperature and pressure boundaries?

　　Sanitization involves circulating 85°C hot water through the module at a maximum pressure of 2.1 bar.The module’s instant hot water capability allows direct introduction of heated water without a slow temperature ramp.A typical sanitization hold time is determined by the overall system design;the module itself tolerates over 150 such cycles with stable performance.

　　7.Does the IONPURE LX-HI require concentrate recirculation and salt injection?

　　No.The module operates with single-pass concentrate flow and does not need concentrate recirculation or brine injection.This reduces system complexity and operational cost,as there are no concentrate recirculation pumps,brine tanks,or associated instrumentation to maintain.

　　8.How many hot water sanitization cycles can the module withstand without performance degradation?

　　Factory testing confirms stable product water quality(conductivity<0.1µS/cm)and pressure drop characteristics after more than 150 hot water sanitization cycles at 85°C.No measurable decline in silica rejection or salt removal efficiency is observed within this validated cycle count.

　　9.What warranty and payment terms apply when purchasing the IONPURE LX-HI?

　　We provide a standard 24-month warranty against manufacturing defects from the date of shipment.Beijing Zhongping Technology accepts payment via T/T and irrevocable L/C at sight;net 30 terms are available for qualified corporate accounts upon credit approval.An extended warranty package is available for an additional fee.

　　10.What import documents and HS code are provided when ordering from Beijing Zhongping Technology?

　　The recommended HS code for electrodeionization modules is 8421.21.We ship international orders under CPT Incoterms and always include the commercial invoice,packing list,certificate of origin,and any required manufacturer certifications needed for customs clearance.Import duties and local taxes are the buyer’s responsibility.